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Studies of the 5′ Exonuclease and Endonuclease Activities of CPSF-73 in Histone Pre-mRNA Processing

Processing of histone pre-mRNA requires a single 3′ endonucleolytic cleavage guided by the U7 snRNP that binds downstream of the cleavage site. Following cleavage, the downstream cleavage product (DCP) is rapidly degraded in vitro by a nuclease that also depends on the U7 snRNP. Our previous studies...

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Main Authors: Yang, Xiao-cui, Sullivan, Kelly D., Marzluff, William F., Dominski, Zbigniew
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612496/
https://ncbi.nlm.nih.gov/pubmed/18955505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00776-08
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