Selective Actions of Novel Allosteric Modulators Reveal Functional Heteromers of Metabotropic Glutamate Receptors in the CNS

Metabotropic glutamate (mGlu) receptors play important roles in regulating CNS function and are known to function as obligatory dimers. Although recent studies have suggested heterodimeric assembly of mGlu receptors in vitro, the demonstration that distinct mGlu receptor proteins can form heterodime...

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Detalhes bibliográficos
Main Authors: Yin, Shen, Noetzel, Meredith J., Johnson, Kari A., Zamorano, Rocio, Jalan-Sakrikar, Nidhi, Gregory, Karen J., Conn, P. Jeffrey, Niswender, Colleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866496/
https://ncbi.nlm.nih.gov/pubmed/24381270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1129-13.2014
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