Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7

Phenotypic studies of mice lacking metabotropic glutamate receptor subtype 7 (mGluR7) suggest that antagonists of this receptor may be promising for the treatment of central nervous system disorders such as anxiety and depression. Suzuki et al. (J Pharmacol Exp Ther 323:147–156, 2007) recently repor...

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Main Authors: Niswender, Colleen M., Johnson, Kari A., Miller, Nicole R., Ayala, Jennifer E., Luo, Qingwei, Williams, Richard, Saleh, Samir, Orton, Darren, Weaver, C. David, Conn, P. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835423/
https://ncbi.nlm.nih.gov/pubmed/20026717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.058768
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