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Functional selectivity induced by mGlu(4) receptor positive allosteric modulation and concomitant activation of G(q) coupled receptors
Metabotropic glutamate receptors (mGlus) are a group of Family C Seven Transmembrane Spanning Receptors (7TMRs) that play important roles in modulating signaling transduction, particularly within the central nervous system. mGlu(4) belongs to a subfamily of mGlus that is predominantly coupled to G(i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412075/ https://ncbi.nlm.nih.gov/pubmed/22426233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.03.003 |
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