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Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu(4)
Using a functional high-throughput screening (HTS) and subsequent solution-phase parallel synthesis approach, we have discovered a novel series of positive allosteric modulators for mGlu(4), a G-protein coupled receptor. This series is comprised of a homopiperazine central core. The solution-phase p...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057427/ https://ncbi.nlm.nih.gov/pubmed/21338051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co1000508 |
| Etiketak: |
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