Modulation of Neurotransmission by GPCRs Is Dependent upon the Microarchitecture of the Primed Vesicle Complex

G(i/o)-protein-coupled receptors (GPCRs) ubiquitously inhibit neurotransmission, principally via Gβγ, which acts via a number of possible effectors. GPCR effector specificity has traditionally been attributed to Gα, based on Gα's preferential effector targeting in vitro compared with Gβγ's...

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Detalhes bibliográficos
Main Authors: Hamid, Edaeni, Church, Emily, Wells, Christopher A., Zurawski, Zack, Hamm, Heidi E., Alford, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866488/
https://ncbi.nlm.nih.gov/pubmed/24381287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3633-12.2014
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