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G protein βγ-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties

Neurotransmitters are thought to be released as quanta, where synaptic vesicles deliver packets of neurotransmitter to the synaptic cleft by fusion with the plasma membrane. However, synaptic vesicles may undergo incomplete fusion. We provide evidence that G protein-coupled receptors inhibit release...

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Main Authors: Photowala, Huzefa, Blackmer, Trillium, Schwartz, Eric, Hamm, Heidi E., Alford, Simon
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449684/
https://ncbi.nlm.nih.gov/pubmed/16537522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600509103
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