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G protein βγ-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties

Neurotransmitters are thought to be released as quanta, where synaptic vesicles deliver packets of neurotransmitter to the synaptic cleft by fusion with the plasma membrane. However, synaptic vesicles may undergo incomplete fusion. We provide evidence that G protein-coupled receptors inhibit release...

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Autors principals: Photowala, Huzefa, Blackmer, Trillium, Schwartz, Eric, Hamm, Heidi E., Alford, Simon
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449684/
https://ncbi.nlm.nih.gov/pubmed/16537522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600509103
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