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G protein βγ-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties

Neurotransmitters are thought to be released as quanta, where synaptic vesicles deliver packets of neurotransmitter to the synaptic cleft by fusion with the plasma membrane. However, synaptic vesicles may undergo incomplete fusion. We provide evidence that G protein-coupled receptors inhibit release...

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Détails bibliographiques
Auteurs principaux: Photowala, Huzefa, Blackmer, Trillium, Schwartz, Eric, Hamm, Heidi E., Alford, Simon
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449684/
https://ncbi.nlm.nih.gov/pubmed/16537522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600509103
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