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Gβγ Binds to the Extreme C Terminus of SNAP25 to Mediate the Action of G(i/o)-Coupled G Protein–Coupled Receptors

G(i/o)-coupled G protein–coupled receptors can exert an inhibitory effect on vesicle release through several G protein–driven mechanisms, more than one of which may be concurrently present in individual presynaptic terminals. The synaptosomal-associated protein of 25 kDa (SNAP25) is a key downstream...

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Опубликовано в: :Mol Pharmacol
Главные авторы: Zurawski, Zack, Rodriguez, Shelagh, Hyde, Karren, Alford, Simon, Hamm, Heidi E.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702098/
https://ncbi.nlm.nih.gov/pubmed/26519224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.101600
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