Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs

Inbred mini-pigs are ideal organ donors for future human xenotransplantations because of their clear genetic background, high homozygosity, and high inbreeding endurance. In this study, we chose fibroblast cells from a highly inbred pig line called Banna mini-pig inbred line (BMI) as donor nuclei fo...

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Detalhes bibliográficos
Main Authors: Xin, Jige, Yang, Huaqiang, Fan, Nana, Zhao, Bentian, Ouyang, Zhen, Liu, Zhaoming, Zhao, Yu, Li, Xiaoping, Song, Jun, Yang, Yi, Zou, Qingjian, Yan, Quanmei, Zeng, Yangzhi, Lai, Liangxue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866186/
https://ncbi.nlm.nih.gov/pubmed/24358349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084250
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