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Generation of multi-gene knockout rabbits using the Cas9/gRNA system

The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) is a simple, robust and efficient technique for gene targeting in model organisms such as zebrafish, mice and rats. In this report, we applied CRISPR technology to rabbits by microinjection of C...

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Detalhes bibliográficos
Publicado no:Cell Regen
Main Authors: Yan, Quanmei, Zhang, Quanjun, Yang, Huaqiang, Zou, Qingjian, Tang, Chengcheng, Fan, Nana, Lai, Liangxue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230364/
https://ncbi.nlm.nih.gov/pubmed/25408890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9769-3-12
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