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Knock-down of Amphiregulin Inhibits Cellular Invasion in Inflammatory Breast Cancer

We have previously shown that SUM-149 human breast cancer cells require an AREG/EGFR autocrine loop for cell proliferation. We also demonstrated that AREG can increase EGFR stability and promote EGFR localization to the plasma membrane. In the present studies we successfully knocked-down AREG expres...

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Detalhes bibliográficos
Main Authors: Baillo, Andrea, Giroux, Craig, Ethier, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865809/
https://ncbi.nlm.nih.gov/pubmed/21302279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22620
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