Oncogenic signaling in amphiregulin and EGFR‐expressing PTEN‐null human breast cancer

A subset of triple negative breast cancer (TNBC) is characterized by overexpression of the epidermal growth factor receptor (EGFR) and loss of PTEN, and patients with these determinants have a poor prognosis. We used cell line models of EGFR‐positive/PTEN null TNBC to elucidate the signaling network...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Kappler, Christiana S., Guest, Stephen T., Irish, Jonathan C., Garrett-Mayer, Elizabeth, Kratche, Zachary, Wilson, Robert C., Ethier, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304881/
https://ncbi.nlm.nih.gov/pubmed/25454348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.10.006
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