Altered EGFR Localization and Degradation in Human Breast Cancer Cells with an Amphiregulin/EGFR Autocrine Loop

The epidermal growth factor receptor (EGFR) and its ligand amphiregulin (AR) have been shown to be co-over expressed in breast cancer. We have previously shown that an AR/EGFR autocrine loop is required for SUM149 human breast cancer cell proliferation, motility and invasion. We also demonstrated th...

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Главные авторы: Willmarth, Nicole E., Baillo, Andrea, Dziubinski, Michele L., Wilson, Kristy, Riese, David J., Ethier, Stephen P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632975/
https://ncbi.nlm.nih.gov/pubmed/18951974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.10.003
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