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MADD is a downstream target of PTEN in triggering apoptosis
Mitogen-activated kinase activating death domain containing protein (MADD) is abundantly expressed in cancer cells and necessary for maintaining cancer cell survival. However, this survival function of MADD is dependent upon its phosphorylation by protein kinase B (Akt). The tumour suppressor PTEN (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865079/ https://ncbi.nlm.nih.gov/pubmed/24038283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24657 |
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