Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells

OBJECTIVE: The clinical utility of TRAIL in the treatment of established human malignancies is limited by the development of resistance to TRAIL. We hypothesized that knockdown of MADD, a TRAIL-resistance factor, may overcome TRAIL resistance in ovarian cancer cells. STUDY DESIGN: MADD expression in...

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Main Authors: LI, Liang-Cheng, JAYARAM, Shankar, GANESH, Lakshmy, QIAN, Lixia, ROTMENSCH, Jacob, MAKER, Ajay V., PRABHAKAR, Bellur S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217125/
https://ncbi.nlm.nih.gov/pubmed/21855847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2011.05.035
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