IG20/MADD Plays a Critical Role in Glucose-Induced Insulin Secretion

Pancreatic β-cell dysfunction is a common feature of type 2 diabetes. Earlier, we had cloned IG20 cDNA from a human insulinoma and had shown that IG20/MADD can encode six different splice isoforms that are differentially expressed and have unique functions, but its role in β-cell function was unexpl...

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Main Authors: Li, Liang-cheng, Wang, Yong, Carr, Ryan, Haddad, Christine Samir, Li, Ze, Qian, Lixia, Oberholzer, Jose, Maker, Ajay V., Wang, Qian, Prabhakar, Bellur S.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2014
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994957/
https://ncbi.nlm.nih.gov/pubmed/24379354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0707
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