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MADD, a Splice Variant of IG20, Is Indispensable for MAPK Activation and Protection against Apoptosis upon Tumor Necrosis Factor-α Treatment
We investigated the physiological role of endogenous MAPK-activating death domain-containing protein (MADD), a splice variant of the IG20 gene, that can interact with TNFR1 in tumor necrosis factor-α (TNFα)-induced activation of NF-κB, MAPK, ERK1/2, JNK, and p38. Using exon-specific short hairpin RN...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679454/ https://ncbi.nlm.nih.gov/pubmed/19289468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808554200 |
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