The p27–Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells

Glucocorticoid therapy is an important treatment modality of hematological malignancies, especially T-cell acute lymphoblastic leukemia (T-ALL). Glucocorticoids are known to induce a cell cycle arrest and apoptosis in T-lymphoma cells. We could demonstrate that the cell cycle arrest induced by the s...

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Main Authors: Kullmann, Michael K, Grubbauer, Claudia, Goetsch, Katrin, Jäkel, Heidelinde, Podmirseg, Silvio R, Trockenbacher, Alexander, Ploner, Christian, Cato, Andrew C.B., Weiss, Carsten, Kofler, Reinhard, Hengst, Ludger
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865052/
https://ncbi.nlm.nih.gov/pubmed/23907123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25622
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