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CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells

Increased use of the glycolytic pathway, even in the presence of oxygen, has recently been recognized as a key characteristic of malignant cells. However, the glycolytic phenotype results in increased lactic acid production and, in order to prevent cellular acidosis, tumor cells must increase proton...

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Autores principales: Walters, Denise K, Arendt, Bonnie K, Jelinek, Diane F
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865013/
https://ncbi.nlm.nih.gov/pubmed/24013424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26193
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