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Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain

The genetic abnormalities underlying multiple myeloma (MM) are notoriously complex and intraclonal heterogeneity is a common disease feature. In the current study, we describe the establishment of a monoclonal IgA kappa (κ) MM cell line, designated MC-B11/14. Cytogenetic and FISH analyses of the ori...

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Foilsithe in:Exp Hematol
Main Authors: Walters, Denise K., Arendt, Bonnie K., Tschumper, Renee C., Wu, Xiaosheng, Jelinek, Diane F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716910/
https://ncbi.nlm.nih.gov/pubmed/29030084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.09.010
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