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CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells
Increased use of the glycolytic pathway, even in the presence of oxygen, has recently been recognized as a key characteristic of malignant cells. However, the glycolytic phenotype results in increased lactic acid production and, in order to prevent cellular acidosis, tumor cells must increase proton...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865013/ https://ncbi.nlm.nih.gov/pubmed/24013424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26193 |
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