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Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation

Tumor metabolism consists of complex interactions between oxygenation states, metabolites, ions, the vascular network and signaling cascades. Accumulation of lactate within tumors has been correlated with poor clinical outcomes. While its production has negative implications, potentially contributin...

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Detalhes bibliográficos
Main Authors: Kennedy, Kelly M, Dewhirst, Mark W
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819205/
https://ncbi.nlm.nih.gov/pubmed/20021214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.145
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