Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides.
Among the pleiotropic effects of aminoglycosides, their irreversible uptake and their blockade of initiating ribosomes have appeared to explain their bactericidal action, while the contributions of translational misreading and membrane damage and the mechanism of that damage have remained uncertain....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.6164 |
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