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Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides.

Among the pleiotropic effects of aminoglycosides, their irreversible uptake and their blockade of initiating ribosomes have appeared to explain their bactericidal action, while the contributions of translational misreading and membrane damage and the mechanism of that damage have remained uncertain....

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Davis, B D, Chen, L L, Tai, P C
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426712/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.6164
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