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Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis.

Tetrahymena thermophila is a eucaryotic organism that is highly susceptible to growth inhibition by aminoglycoside antibiotics. Concentrations of paromomycin, gentamicin G418, and hygromycin B at 22, 10, and 17 microM, respectively, inhibited growth by 50%. A combination of in vitro and in vivo meth...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Eustice, D C, Wilhelm, J M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6433789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.1.53
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