Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides.
Among the pleiotropic effects of aminoglycosides, their irreversible uptake and their blockade of initiating ribosomes have appeared to explain their bactericidal action, while the contributions of translational misreading and membrane damage and the mechanism of that damage have remained uncertain....
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1986
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.6164 |
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