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The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups

Over the past decade, large strides have been achieved in the invention of methods for the direct enantioselective addition of alkynes and metal alkynylide nucleophiles into prochiral aldehydes, ketones, and imines. This review highlights and compares the available methods for these transformations.

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Bibliographic Details
Main Authors: Trost, Barry M., Weiss, Andrew H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864370/
https://ncbi.nlm.nih.gov/pubmed/24353484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.200800776
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