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The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups

Over the past decade, large strides have been achieved in the invention of methods for the direct enantioselective addition of alkynes and metal alkynylide nucleophiles into prochiral aldehydes, ketones, and imines. This review highlights and compares the available methods for these transformations.

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Detalhes bibliográficos
Main Authors: Trost, Barry M., Weiss, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864370/
https://ncbi.nlm.nih.gov/pubmed/24353484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.200800776
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