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Direct Asymmetric Michael Addition to Nitroalkenes: Vinylogous Nucleophilicity Under Dinuclear Zinc Catalysis

[Image: see text] Under dinuclear catalysis, the direct conjugate addition of 2(5H)-furanone to nitroalkenes involves the γ-position of the nucleophile. The synthetically versatile Michael adducts are prepared in good yields, with high levels of diastereo- and enantioselectivity. A model is presente...

詳細記述

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書誌詳細
主要な著者: Trost, Barry M., Hitce, Julien
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679032/
https://ncbi.nlm.nih.gov/pubmed/19281239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809723u
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