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Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia
Several distinct congenital disorders can lead to tissue-iron overload with anemia. Repeated blood transfusions are one of the major causes of iron overload in several of these disorders, including β-thalassemia major, which is characterized by a defective β-globin gene. In this state, hyperabsorpti...
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| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864280/ https://ncbi.nlm.nih.gov/pubmed/24282296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314197110 |
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