Toward a Network Model of MHC Class II-Restricted Antigen Processing

The standard model of Major Histocompatibility Complex class II (MHCII)-restricted antigen processing depicts a straightforward, linear pathway: internalized antigens are converted into peptides that load in a chaperone dependent manner onto nascent MHCII in the late endosome, the complexes subseque...

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Bibliographic Details
Main Authors: Miller, Michael A., Ganesan, Asha Purnima V., Eisenlohr, Laurence C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864185/
https://ncbi.nlm.nih.gov/pubmed/24379819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00464
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