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Alternative Generation of MHC Class II-Restricted Epitopes. Not So Exceptional?
By convention, peptides presented at the cell surface by MHC class II molecules (MHCII) are derived from internalized (“exogenous”) antigen that is denatured and fragmented in the endocytic compartment and loaded onto MHC in the late endosome with the assistance of the H2-DM chaperone. Over the past...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610803/ https://ncbi.nlm.nih.gov/pubmed/23200635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.020 |
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