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Giving CD4+ T Cells the Slip: Viral Interference with MHC Class II-Restricted Antigen Processing and Presentation

Activation of CD4+ T cells through interactions with peptides bound to Major Histocompatibility Complex Class II (MHC-II) molecules is a crucial step in clearance of most pathogens. Consequently, many viruses have evolved ways of blocking this aspect of adaptive immunity, from specific targeting of...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Forsyth, Katherine S., Eisenlohr, Laurence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894315/
https://ncbi.nlm.nih.gov/pubmed/27115617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.03.003
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