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Mapping and restriction of a dominant viral CD4(+) T cell core epitope by both MHC class I and MHC class II

Virus-specific CD4(+) T cells contribute to effective virus control through a multiplicity of mechanisms including direct effector functions as well as “help” for B cell and CD8(+) T cell responses. Here, we have used the lymphocytic choriomeningitis virus (LCMV) system to assess the minimal constra...

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Autors principals: Homann, Dirk, Lewicki, Hanna, Brooks, David, Eberlein, Jens, Mallet-Designé, Valerie, Teyton, Luc, Oldstone, Michael B.A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976554/
https://ncbi.nlm.nih.gov/pubmed/17320138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.12.025
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