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Hydrophobicity as a driver of MHC class I antigen processing

The forces that drive conversion of nascent protein to major histocompatibility complex (MHC) class I-restricted peptides remain unknown. We explored the fundamental property of overt hydrophobicity as such a driver. Relocation of a membrane glycoprotein to the cytosol via signal sequence ablation r...

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Detalhes bibliográficos
Main Authors: Huang, Lan, Kuhls, Matthew C, Eisenlohr, Laurence C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102268/
https://ncbi.nlm.nih.gov/pubmed/21378750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.62
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