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Hydrophobicity as a driver of MHC class I antigen processing
The forces that drive conversion of nascent protein to major histocompatibility complex (MHC) class I-restricted peptides remain unknown. We explored the fundamental property of overt hydrophobicity as such a driver. Relocation of a membrane glycoprotein to the cytosol via signal sequence ablation r...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102268/ https://ncbi.nlm.nih.gov/pubmed/21378750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.62 |
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