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β-Adrenergic Regulation of the L-type Ca(2+) Channel does not Require Phosphorylation of α(1C) Ser(1700)

RATIONALE: Sympathetic nervous system triggered activation of protein kinase A (PKA), which phosphorylates several targets within cardiomyocytes, augments inotropy, chronotropy and lusitopy. An important target of β-adrenergic stimulation is the sarcolemmal L-type Ca(2+) channel, Ca(V)1.2, which pla...

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Hlavní autoři: Yang, Lin, Katchman, Alexander, Samad, Tahmina, Morrow, John, Weinberg, Richard, Marx, Steven O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864014/
https://ncbi.nlm.nih.gov/pubmed/23825359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301926
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