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β-Adrenergic Regulation of the L-type Ca(2+) Channel does not Require Phosphorylation of α(1C) Ser(1700)
RATIONALE: Sympathetic nervous system triggered activation of protein kinase A (PKA), which phosphorylates several targets within cardiomyocytes, augments inotropy, chronotropy and lusitopy. An important target of β-adrenergic stimulation is the sarcolemmal L-type Ca(2+) channel, Ca(V)1.2, which pla...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864014/ https://ncbi.nlm.nih.gov/pubmed/23825359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301926 |
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