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Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells.
Detergent-soluble DNA is the fraction (2-4%) of DNA that is released into the supernate upon mild detergent lysis. It is nonmitochondrial in origin. It labels efficiently with deoxy[3H]ribonucleosides and the labeling is prevented by inhibitors of polymerase alpha and ribonucleotide reductase. In pr...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5871 |
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