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Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

We have utilized antibody probes to examine the expression of DNA topoisomerases I and II and chromosome scaffold protein Sc-2 in normal and transformed cells. Neither topoisomerase I nor Sc-2 shows significant fluctuations in content or stability across the cell cycle. In contrast, topoisomerase II...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Heck, M M, Hittelman, W N, Earnshaw, W C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279709/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829215/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1086
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