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Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

We have utilized antibody probes to examine the expression of DNA topoisomerases I and II and chromosome scaffold protein Sc-2 in normal and transformed cells. Neither topoisomerase I nor Sc-2 shows significant fluctuations in content or stability across the cell cycle. In contrast, topoisomerase II...

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Autores principales: Heck, M M, Hittelman, W N, Earnshaw, W C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC279709/
https://ncbi.nlm.nih.gov/pubmed/2829215
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