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Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

We have isolated two genes from yeast encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase [hydroxymethylglutaryl-coenzyme A reductase (NADPH); HMG-CoA reductase; EC 1.1.1.34], the rate-limiting enzyme of sterol biosynthesis. These genes, HMG1 and HMG2, were identified by hybridization to a cDNA...

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Dettagli Bibliografici
Autori principali: Basson, M E, Thorsness, M, Rine, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC386328/
https://ncbi.nlm.nih.gov/pubmed/3526336
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