Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis.

The pathway of sterol biosynthesis is highly conserved in all eucaryotic cells. We demonstrated structural and functional conservation of the rate-limiting enzyme of the mammalian pathway, 3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA reductase), between the yeast Saccharomyces cerevisia...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Basson, M E, Thorsness, M, Finer-Moore, J, Stroud, R M, Rine, J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1988
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3065625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.9.3797-3808.1988
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