Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Both 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozymes of the yeast Saccharomyces cerevisiae are predicted to contain seven membrane-spanning domains. Previous work had established the utility of the histidinol dehydrogenase protein domain, encoded by HIS4C, as a topologically sensi...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Sengstag, C, Stirling, C, Schekman, R, Rine, J
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1990
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405252/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.672
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