Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Both 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozymes of the yeast Saccharomyces cerevisiae are predicted to contain seven membrane-spanning domains. Previous work had established the utility of the histidinol dehydrogenase protein domain, encoded by HIS4C, as a topologically sensi...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Sengstag, C, Stirling, C, Schekman, R, Rine, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.672-680.1990
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