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Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

We have isolated two genes from yeast encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase [hydroxymethylglutaryl-coenzyme A reductase (NADPH); HMG-CoA reductase; EC 1.1.1.34], the rate-limiting enzyme of sterol biosynthesis. These genes, HMG1 and HMG2, were identified by hybridization to a cDNA...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Basson, M E, Thorsness, M, Rine, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3526336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.15.5563
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