Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response

Recent candidate gene studies using a human liver bank and in vivo validation in healthy volunteers identified polymorphisms in cytochrome P450 (CYP) 3A4 gene (CYP3A4*22), Ah-receptor nuclear translocator (ARNT), and peroxisome proliferator-activated receptor-α (PPAR-α) genes that are associated wit...

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Bibliographic Details
Main Authors: Kreutz, Rolf P, Owens, Janelle, Jin, Yan, Nystrom, Perry, Desta, Zeruesenay, Kreutz, Yvonne, Breall, Jeffrey A, Li, Lang, Chiang, ChienWei, Kovacs, Richard J, Flockhart, David A
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862586/
https://ncbi.nlm.nih.gov/pubmed/24353446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S53151
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