Establishment of anti-tumor memory in humans using in vitro-educated CD8(+) T cells

While advanced stage melanoma patients have a median survival of less than a year, adoptive T cell therapy can induce durable clinical responses in some patients. Successful adoptive T cell therapy to treat cancer requires engraftment of anti-tumor T lymphocytes that not only retain specificity and...

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Hauptverfasser: Butler, Marcus O., Friedlander, Philip, Milstein, Matthew I., Mooney, Mary M., Metzler, Genita, Murray, Andrew P., Tanaka, Makito, Berezovskaya, Alla, Imataki, Osamu, Drury, Linda, Brennan, Lisa, Flavin, Marisa, Neuberg, Donna, Stevenson, Kristen, Lawrence, Donald, Hodi, F. Stephen, Velazquez, Elsa F., Jaklitsch, Michael T., Russell, Sara E., Mihm, Martin, Nadler, Lee M., Hirano, Naoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861895/
https://ncbi.nlm.nih.gov/pubmed/21525398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002207
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