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The Wing of a Winged Helix-Turn-Helix Transcription Factor Organizes the Active Site of BirA, a Bifunctional Repressor/Ligase
The BirA biotin protein ligase of Escherichia coli belongs to the winged helix-turn-helix (wHTH) family of transcriptional regulators. The N-terminal BirA domain is required for both transcriptional regulation of biotin synthesis and biotin protein ligase activity. We addressed the structural and fu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861651/ https://ncbi.nlm.nih.gov/pubmed/24189073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525618 |
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