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Altered Regulation of Escherichia coli Biotin Biosynthesis in BirA Superrepressor Mutant Strains

Transcription of the Escherichia coli biotin (bio) operon is directly regulated by the biotin protein ligase BirA, the enzyme that covalently attaches biotin to its cognate acceptor proteins. Binding of BirA to the bio operator requires dimerization of the protein, which is triggered by BirA-catalyz...

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Bibliographic Details
Main Authors: Chakravartty, Vandana, Cronan, John E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294782/
https://ncbi.nlm.nih.gov/pubmed/22210766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06549-11
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