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The Staphylococcus aureus group II biotin protein ligase BirA is an effective regulator of biotin operon transcription and requires the DNA binding domain for full enzymatic activity

Group II biotin protein ligases (BPLs) are characterized by the presence of an N-terminal DNA binding domain that functions in transcriptional regulation of the genes of biotin biosynthesis and transport. The Staphylococcus aureus Group II BPL which is called BirA has been reported to bind an imperf...

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Publicat a:Mol Microbiol
Autors principals: Henke, Sarah K., Cronan, John E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116234/
https://ncbi.nlm.nih.gov/pubmed/27445042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13470
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